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Radioimmunotherapy for Chronic Lymphocytic Leukemia
Study Summary
This trial is testing a new cancer treatment to see if it is safe and effective.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
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Who is running the clinical trial?
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- I have had 4 or fewer previous cancer treatments.My kidney and liver functions are within the required limits.My cancer has worsened within a year after receiving high-dose radiation.I am currently taking medication for cancer, either approved or experimental.I haven't taken chemotherapy or immunosuppressants in the last 4 weeks.I do not have severe heart disease or other serious illnesses that would interfere with the study.I have a kidney blockage causing swelling.I am not pregnant or nursing and agree to use birth control during and for 6 months after treatment.I am currently receiving IV treatment for an infection.My condition is diagnosed as intermediate or high-risk B-cell CLL.My cancer did not respond or got worse after chemotherapy or biologic therapy.I have been treated with a medicine related to purine nucleoside.I can care for myself but may need occasional help, and my doctor expects me to live at least 3 more months.I had cancer before, but it wasn't CLL, skin cancer, or in situ cervical cancer, and I've been free of it for over 5 years.My leukemia cells test positive for CD20.My blood tests show enough granulocytes and platelets for the study's requirements.
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
To be a part of this research, what are the basic requirements a person must meet?
"This clinical trial is looking for 30 people with leukemia between the ages of 18 and 0. Most notable, candidates are required to meet the following criteria: Patients must have a Karnofsky Performance status of at least 60% and an anticipated survival of at least 3 months., Patients must fulfill the criteria for the diagnosis of intermediate-risk B-cell CLL or high-risk B-cell CLL, The bone marrow aspirate must demonstrate that greater than or equal to 30% of all nucleated cells are lymphoid., Patients must have evidence that their leukemic lymphocytes express the CD20 antigen., Patients must have been previously treated"
Does the age limit for this research project exclude people in their early forties?
"The age limit to qualify for this trial is 18 years old. Out of the 2123 total trials, this one is unique in that it only includes patients who are 18 years old or younger."
How does this treatment's safety record compare to other available options?
"Since this is a Phase 1 trial, there is only preliminary data supporting the safety of this treatment. Consequently, our team at Power has given it a 1."
Are people with the ailment under study able to participate in the trial at this time?
"The study in question is not currently looking for candidates, as seen on clinicaltrials.gov. This site was last updated on June 23rd, 2005, and was posted on July 1st, 1999. However, there are many other trials (1570) that are currently looking for patients."
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