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Crosslinking Agent

PXL-330 Platinum device for crosslinking with Peschke riboflavin solution for Corneal Ectasia

Phase 1
Waitlist Available
Led By Tyrone McCall, MD
Research Sponsored by Cornea Associates of Texas
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
8 years of age or older
Signed written informed consent
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 12 months
Awards & highlights

Study Summary

This trial found that the PXL-Platinum 330 System is safe and effective for corneal collagen cross-linking in eyes with corneal thinning conditions.

Eligible Conditions
  • Pellucid Marginal Corneal Degeneration
  • Corneal Ectasia
  • Corneal Dystrophy
  • Keratoconus

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
You are willing and able to comply with follow-up visits.
Select...
The corneal apex is not decentlyered.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~12 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
K-Max
K-Mean
Secondary outcome measures
Best Corrected Visual Acuity
Central Pachymetry
Uncorrected Visual Acuity

Trial Design

2Treatment groups
Experimental Treatment
Group I: Pulsed 6mW/cm2Experimental Treatment1 Intervention
6mW/cm2, with pulsed mode, 10 seconds on, 10 second off, for 30 minute total treatment time
Group II: Pulsed 4mW/cm2Experimental Treatment1 Intervention
4mW/cm2, with pulsed mode, 10 seconds on, 10 second off, for 45 minute total treatment time
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Riboflavin
FDA approved

Find a Location

Who is running the clinical trial?

Cornea Associates of TexasLead Sponsor
1 Previous Clinical Trials
1,000 Total Patients Enrolled
Tyrone McCall, MDPrincipal InvestigatorCornea Associates of Texas

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Who else is applying?

What state do they live in?
Texas
How old are they?
18 - 65
What site did they apply to?
Cornea Associates of Texas
What portion of applicants met pre-screening criteria?
Met criteria
~39 spots leftby Mar 2025