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Inhaled Anesthetics
Isoflurane for Heart Disease
Phase 1
Waitlist Available
Led By Kathirvel Subramaniam, MD, MSc
Research Sponsored by Kathirvel Subramaniam
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up intraoperative period during cardiac surgery before initiation of cardiopulmonary bypass
Awards & highlights
Study Summary
This trial will compare the effects of sevoflurane and isoflurane on the heart, using a special imaging software to measure heart function.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ intraoperative period during cardiac surgery before initiation of cardiopulmonary bypass
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~intraoperative period during cardiac surgery before initiation of cardiopulmonary bypass
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Global longitudinal strain of myocardium, unitless (Comparison between two inhalational anesthetics, isoflurane and sevoflurane)
Secondary outcome measures
Global longitudinal strain of myocardium, unitless (Dose dependent effect of isoflurane)
Global longitudinal strain of myocardium, unitless (Dose dependent effect of sevoflurane)
Trial Design
1Treatment groups
Experimental Treatment
Group I: Sevoflurane then isofluraneExperimental Treatment2 Interventions
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Isoflurane
2010
Completed Phase 4
~53840
Sevoflurane
2016
Completed Phase 4
~1260
Find a Location
Who is running the clinical trial?
Kathirvel SubramaniamLead Sponsor
5 Previous Clinical Trials
816 Total Patients Enrolled
Kathirvel Subramaniam, MD, MScPrincipal Investigator - University of Pittsburgh
University of Pittsburgh
Frequently Asked Questions
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