Your session is about to expire
← Back to Search
Probenecid for Alcohol Use Disorder (PROB Trial)
PROB Trial Summary
This trial tests the effects of probenecid, given as a single 2g dose, on alcohol intoxication in humans. The trial is double-blind, meaning that neither the participants nor the staff administering the drug will know who is receiving probenecid or placebo. The study is also placebo-controlled, meaning that a group of participants will receive a placebo (a 'sugar pill') instead of probenecid.
PROB Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowPROB Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2020 Phase 4 trial • 8 Patients • NCT03965351PROB Trial Design
Find a Location
Who is running the clinical trial?
Frequently Asked Questions
What potential adverse effects can be associated with Probenecid usage?
"Probenecid's safety was rated a 1 due to the limited research and data associated with Phase 1 trials."
How many participants are being monitored for this research endeavor?
"Affirmative. Clinicaltrials.gov indicates that this scientific research, which was initially posted on December 2nd 2020, is actively searching for volunteers. Approximately 34 participants must be solicited from 1 clinical setting."
Is this investigation currently enrolling participants?
"According to clinicaltrials.gov, recruitment for this trial is actively underway having been first posted on December 2nd 2020 and most recently edited on July 18th 2022."
Who is able to qualify to join this clinical trial?
"To meet the criteria for this study, individuals should have a history of alcohol usage and be between 21 to 70 years old. Accordingly, 34 applicants are being recruited."
In what circumstances is Probenecid usually prescribed?
"Probenecid can be employed to manage gouty arthritis, arthritis, gouty and hyperuricemia."
Are there prior investigations that have examined Probenecid?
"Currently, 3 Probenecid trials are in progress with 2 of them at the final Phase 3 stage. While many occur near Providence, Rhode island, 4 locations overall are hosting these clinical studies."
Is the elderly cohort being included in this exploration of treatment options?
"To qualify for this particular trial, individuals must be between 21 and 70 years old. There are 33 trials geared towards people younger than 18, and 252 studies available to those aged 65 or older."
Who else is applying?
What state do they live in?
What site did they apply to?
What portion of applicants met pre-screening criteria?
How many prior treatments have patients received?
Share this study with friends
Copy Link
Messenger