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Nonsteroidal Anti-inflammatory Drug

Ketorolac Tromethamine for Breast Reconstruction

Phase 1
Waitlist Available
Led By James Thompson
Research Sponsored by Carilion Clinic
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Patient consents to study
Adult females needing breast reconstruction or breast reduction (day surgeries)
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2 weeks to 90 days post operation
Awards & highlights

Study Summary

This trial will study whether giving ketorolac before breast surgery can reduce post-operative pain and the amount of opioids needed afterwards.

Eligible Conditions
  • Breast Reduction
  • Breast Reconstruction

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2 weeks to 90 days post operation
This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 weeks to 90 days post operation for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change of post-operative pain: Likert scale
Secondary outcome measures
Change of narcotic use
Complication assessment

Trial Design

3Treatment groups
Experimental Treatment
Placebo Group
Group I: Low Dose (15mg) ToradolExperimental Treatment1 Intervention
15mg ketorolac (toradol) administered during surgery
Group II: High Dose (30mg) ToradolExperimental Treatment1 Intervention
30mg ketorolac (toradol) administered during surgery
Group III: ControlPlacebo Group1 Intervention
Saline injection administered during surgical procedure
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Ketorolac
FDA approved

Find a Location

Who is running the clinical trial?

Carilion ClinicLead Sponsor
70 Previous Clinical Trials
12,532 Total Patients Enrolled
James ThompsonPrincipal InvestigatorCarilion Clinic
1 Previous Clinical Trials
40 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Do I fulfill the requirements for participation in this research endeavor?

"This research is looking for 183 women aged 18-64 who are seeking breast reduction or reconstruction. The key eligibility criteria include an adult female patient consenting to the clinical trial."

Answered by AI

What potential hazards exist when ingesting Ketorolac Tromethamine?

"Because the trial is in its opening stages, with limited data on safety and efficacy available, Ketorolac Tromethamine received a score of 1."

Answered by AI

What is the current tally of participants in this experiment?

"Affirmative. Clinicaltrials.gov provides evidence that this clinical experiment is actively enrolling individuals, with first postings beginning on June 22nd 2020 and most recent revisions occuring May 4th 2021. This research study seeks 183 participants from one location."

Answered by AI

Are participants beyond the age of sixty being considered for this experiment?

"This research initiative is currently seeking adult participants with ages ranging from 18 to 64."

Answered by AI

Are there still available slots to join this research endeavor?

"True. According to the information hosted on clinicaltrials.gov, patient recruitment has begun for this trial that was initially posted on June 22nd 2020 and last updated May 4th 2021. A total of 183 patients are needed at a single site."

Answered by AI

Is there a history of research surrounding Ketorolac Tromethamine?

"Presently, 38 medical trials are being conducted to research Ketorolac Tromethamine. 8 of these ongoing investigations are in Phase 3 and 57 locations across the globe have sites running experiments for this medication. Los Angeles is particularly active with regards to studies about its efficacy."

Answered by AI

In what circumstances is Ketorolac Tromethamine typically prescribed?

"Ketorolac Tromethamine is often used to alleviate ocular itching. It has also been shown to provide temporary relief for pain, facilitate the induction of a nerve block and regulate pupil size."

Answered by AI
~39 spots leftby Mar 2025