This trial will study if smokers who switch to cigarettes with very low nicotine content will have changes in the brain circuits involved in craving and self-control.
- Tobacco Addiction
1 Primary · 0 Secondary · Reporting Duration: Changes in BOLD from baseline to the 6-week visit.
Side Effects for
2 Treatment Groups
Very low nicotine content cigarettes
1 of 2
Normal nicotine content cigarettes
1 of 2
90 Total Participants · 2 Treatment Groups
Primary Treatment: Very low nicotine content cigarettes · Has Placebo Group · Phase < 1
Who is running the clinical trial?
Age 21 - 60 · All Participants · 10 Total Inclusion CriteriaMark “Yes” if the following statements are true for you:
Frequently Asked Questions
Are minors authorized to participate in this clinical experimentation?
"As per the restrictions, only persons aged 21 to 60 are eligible for enrollment in this clinical trial." - Anonymous Online Contributor
Is there a possibility for eligible individuals to join this experiment?
"Affirmative. Per information on clinicaltrials.gov, this medical trial is actively recruiting participants; the first listing was made on February 20th 2020 and it has been revised as recently as March 25th 2022. The research team requires a total of 90 individuals to take part in the study from one specific site." - Anonymous Online Contributor
Who may participate in the current clinical exploration?
"This clinical trial is seeking 90 individuals addicted to tobacco, aged between 21 and 60. There are a number of prerequisites for enrolment, such as smoking at least 5 cigarettes daily; residing in the local vicinity for 3 months; 1 year or more of nicotine usage without cessation attempts; comprehending and consenting to research protocols; abstaining from pregnancy/nursing via contraception measures; access to an internet-enabled computer with Zoom capabilities; having no higher than high school education or earning less than $50k annually. In addition, applicants must not have attempted quitting within 1 month prior nor plan on doing so over the following 3 months" - Anonymous Online Contributor
What is the capacity of enrollment in this clinical trial?
"Affirmative. The clinical trial, which was initially advertised on February 20th 2020, is still recruiting patients as per the information hosted on clinicaltrials.gov and last updated on March 25th 2022. They are looking for 90 participants to enroll at one location." - Anonymous Online Contributor
What other experimentations have been conducted using Very low nicotine content cigarettes?
"As of now, 71 clinical trials for Very low nicotine content cigarettes are being conducted. Of those, 5 have reached the third phase of study. The majority of these research sites are based in Greenville, South Carolina; however there is a total number of 204 locations managing experiments related to this treatment." - Anonymous Online Contributor