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MRI for Movement Disorders

Phase < 1
Waitlist Available
Led By Mark Hallett, M.D.
Research Sponsored by National Institute of Neurological Disorders and Stroke (NINDS)
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
General Inclusion Criteria for PNES patients:
General Inclusion Criteria for FMD patients:
Timeline
Screening 3 weeks
Treatment Varies
Follow Up throughout
Awards & highlights

Study Summary

This trial is studying how the mind and brain work together to cause episodes of uncontrolled shaking in people with no known underlying brain or medical disorder.

Eligible Conditions
  • Movement Disorders

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
This is a list of things that make someone eligible to participate in the study if they have PNES (psychogenic non-epileptic seizures).
Select...
Anyone with fibromuscular dysplasia (FMD) can participate.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~throughout
This trial's timeline: 3 weeks for screening, Varies for treatment, and throughout for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Anatomical MRI: VBM
Genetics: S/S genotype of the serotonin transporter promoter region polymorphism.
fMRI study: blood oxygenation level dependent (BOLD) signal in the regions of interest during a gender identification task

Trial Design

1Treatment groups
Experimental Treatment
Group I: fMRI studyExperimental Treatment1 Intervention
subjects receiving MRI
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
MRI
2009
Completed Phase 2
~1370

Find a Location

Who is running the clinical trial?

National Institute of Neurological Disorders and Stroke (NINDS)Lead Sponsor
1,337 Previous Clinical Trials
648,590 Total Patients Enrolled
37 Trials studying Movement Disorders
16,178 Patients Enrolled for Movement Disorders
Mark Hallett, M.D.Principal InvestigatorNational Institute of Neurological Disorders and Stroke (NINDS)
40 Previous Clinical Trials
6,541 Total Patients Enrolled
8 Trials studying Movement Disorders
1,429 Patients Enrolled for Movement Disorders
Hyun Joo Cho, M.D.Principal InvestigatorNational Institute of Neurological Disorders and Stroke (NINDS)
2 Previous Clinical Trials
108 Total Patients Enrolled
1 Trials studying Movement Disorders
50 Patients Enrolled for Movement Disorders

Media Library

MRI Clinical Trial Eligibility Overview. Trial Name: NCT00500994 — Phase < 1
Movement Disorders Research Study Groups: fMRI study
Movement Disorders Clinical Trial 2023: MRI Highlights & Side Effects. Trial Name: NCT00500994 — Phase < 1
MRI 2023 Treatment Timeline for Medical Study. Trial Name: NCT00500994 — Phase < 1

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any prerequisite qualifications for involvement in this experiment?

"This medical trial seeks 366 participants diagnosed with etat marbre and aged between 18-90 years old. Patients must meet the following requirements: Be of legal age, have a neurologist confirm their clinical definite FMD using Fahn and Williams criteria, and possess a diagnosis for PNES based on 24 hour video-EEG recording without concurrent EEG changes that is certified by a neurologist."

Answered by AI

How many participants can be accommodated in this research program?

"Affirmative. According to clinicaltrials.gov, this medical experiment commenced on October 5th 2007 and was recently modified on November 19th 2022. 366 patients must be enrolled from 2 distinct sites in order for the study to continue being conducted."

Answered by AI

Are there still openings available in this research project?

"Affirmative. According to the data on clinicaltrials.gov, this clinical trial is open for recruitment and was initially posted on October 5th 2007 with its most recent update being November 19th 2022. 366 participants are needed from 2 distinct medical centres."

Answered by AI

Does the study have an age limit, and if so, to what extent?

"The age range for participation in this study has been set between 18 and 90 years of age."

Answered by AI
~15 spots leftby Mar 2025