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Eribulin Mesylate for Brain Cancer
Study Summary
This trial is studying how well eribulin mesylate collects in brain tumors to see if it can help treat them.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- You have a serious heart rhythm problem or a condition that causes your heart's electrical system to not work properly.You have not fully recovered from the side effects of your previous chemotherapy or radiation treatment.You have severe heart failure, unstable angina, or have had a heart attack in the last 6 months.You are unable to have a brain MRI.You have severe nerve problems in your arms or legs.You have a serious infection that needs to be treated with antibiotics, antivirals, or antifungals.Your absolute neutrophil count is higher than 1500 cells per cubic millimeter.Your platelet count is higher than 100,000 cells per cubic millimeter.Your kidney function test shows a normal level of creatinine in your blood.Your total bilirubin level is less than 2.0 mg/dl.You should be able to perform daily activities with a performance status of 60 or higher, according to a scale called Karnofsky.If a patient has MRI results showing a possible tumor but hasn't been diagnosed with cancer yet, they can sign the consent form. However, their final eligibility for the study will depend on the results of a tissue sample taken during surgery.You have had treatment for your brain tumor in the past, including radiation, surgery, or chemotherapy. There is no limit to the number of chemotherapy treatments you have had.Patients who have taken eribulin before can only take part in the microdialysis part of the study.Your AST level in the blood is less than three times the normal limit.Your ALT level in the blood is not more than three times the normal limit for the laboratory where the test is done.You need to wait for a specific amount of time after finishing your last chemotherapy before starting the new treatment with eribulin, based on the time it takes for the chemotherapy to leave your body.You are planning to have surgery or biopsy to find out if your brain tumor is getting worse or if it's just a side effect of your treatment.
- Group 1: Treatment (eribulin mesylate)
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Are there any available vacancies in this exploration of treatments?
"This clinical trial is not accepting participants, as it was last edited on March 16th 2022. However, those seeking to join a medical study can look for other options; 2702 trials are open for brain cancer patients and 37 studies require Microdialysis volunteers."
What is the upper limit to participant enrollment in this clinical experiment?
"This particular trial is not currently accepting participants, having been last updated on March 16th of 2022. Nonetheless, 2702 clinical trials related to brain cancer and 37 studies pertaining to Microdialysis are actively enrolling patients who meet the criteria."
Have any prior experiments examined the effects of Microdialysis?
"At the moment, 37 clinical trials researching Microdialysis are in progress with 10 of them being conducted at Phase 3. Although some studies are located in Plano, Texas - 1,225 different sites worldwide have active research projects revolving around this topic."
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