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Ubiquinone for Myocardial Injury (ACE Trial)

Phase < 1
Waitlist Available
Research Sponsored by Minneapolis Veterans Affairs Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
ELECTIVE HIGH RISK NON-CARDIAC SURGERY
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1 year
Awards & highlights

ACE Trial Summary

This study is evaluating whether a drug called CoQ10 can reduce the amount of a biomarker called NT-Pro BNP in people with heart disease.

Eligible Conditions
  • Myocardial Injury

ACE Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

ACE Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 year
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
BNP levels following surgery
Cardiac Troponin levels following surgery
Change in Troponin levels from baseline to peak
+1 more
Secondary outcome measures
Length of stay
Number of participants requiring coronary revascularization
Number of participants who died
+5 more

ACE Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: UbiquinoneExperimental Treatment1 Intervention
Take oral tablets as directed (2x200 mg for 3 days prior to surgery)
Group II: PlaceboPlacebo Group1 Intervention
Take oral tablets as directed (2x200 mg for 3 days prior to surgery)
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Ubidecarenone
FDA approved

Find a Location

Who is running the clinical trial?

Minneapolis Veterans Affairs Medical CenterLead Sponsor
71 Previous Clinical Trials
14,561 Total Patients Enrolled
EDWARD MCFALLS, MDStudy ChairSITE PI

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
~29 spots leftby Mar 2025