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Ubiquinone for Myocardial Injury (ACE Trial)
Phase < 1
Waitlist Available
Research Sponsored by Minneapolis Veterans Affairs Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
ELECTIVE HIGH RISK NON-CARDIAC SURGERY
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1 year
Awards & highlights
ACE Trial Summary
This study is evaluating whether a drug called CoQ10 can reduce the amount of a biomarker called NT-Pro BNP in people with heart disease.
Eligible Conditions
- Myocardial Injury
ACE Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowACE Trial Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 1 year
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 year
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
BNP levels following surgery
Cardiac Troponin levels following surgery
Change in Troponin levels from baseline to peak
+1 moreSecondary outcome measures
Length of stay
Number of participants requiring coronary revascularization
Number of participants who died
+5 moreACE Trial Design
2Treatment groups
Experimental Treatment
Placebo Group
Group I: UbiquinoneExperimental Treatment1 Intervention
Take oral tablets as directed (2x200 mg for 3 days prior to surgery)
Group II: PlaceboPlacebo Group1 Intervention
Take oral tablets as directed (2x200 mg for 3 days prior to surgery)
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Ubidecarenone
FDA approved
Find a Location
Who is running the clinical trial?
Minneapolis Veterans Affairs Medical CenterLead Sponsor
71 Previous Clinical Trials
14,561 Total Patients Enrolled
EDWARD MCFALLS, MDStudy ChairSITE PI
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
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