This trial tests PhytoSERM, a plant-based supplement that mimics estrogen, in peri- and postmenopausal women. The goal is to see if it helps the brain use glucose better, potentially improving brain function and reducing menopausal symptoms. Participants will take the supplement for several months, with brain scans before and after to measure effects. PhytoSERM is a formulation of genistein, daidzein, and S-equol that may enhance neuron function and estrogenic mechanisms in the brain.