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Hormone Therapy
Low-Carb, High-Unsaturated Fat Diet for Obesity
Recruiting1 award
Stanford, California
This trial is testing the hypothesis that in obese, insulin-resistant individuals, a diet lower in carbohydrate and higher in mono/polyunsaturated fats will lead to greater weight loss and reduction in CHD risk factors, as compared to a standard hypocaloric diet. Additionally, the trial will compare diabetics treated with insulin secretagogues (drugs that increase insulin secretion) to diabetics treated with insulin sensitizers (drugs that decrease insulin concentrations) to see if there are differences in weight loss, change in insulin resistance, blood pressure, lipid and lipoproteins, markers of endothelial function, daylong insulin and glucose
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