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Behavioral Intervention
Chronotherapy for Perinatal Depression
Recruiting1 award
Chapel Hill, North Carolina
This trial is testing whether a non-pharmacological treatment called Personalized Integrated Chronotherapy (PIC) can improve outcomes for pregnant women with depression and anxiety. The study will enroll expectant mothers who will be randomized to either: (a) usual care (UC, n = 110) or (b) PIC+UC (n = 110). PIC+UC will have pregnancy and postpartum components and will be administered via a personalized approach tailored to optimize the intervention based on each patient's individual circadian and sleep timing. The study will assess whether PIC is effective in improving mood symptoms and will also examine the target mechanisms by which
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