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Chemotherapy
HC-5404-FU Dose Determination for Solid Cancers
Recruiting1 awardPhase 1
Saint Paul, Minnesota
This trial is testing a new drug, HC-5404-FU, to see what the maximum tolerated dose is and to evaluate its safety and tolerability. The trial will enroll 36 subjects with specific types of cancer at 3-5 US sites. The starting dose is 25 mg twice daily, escalating to 50, 100, and 200 mg as safety allows. The trial will then expand to assess the most appropriate dose and tumor type(s) selected in Phase 1a as the most appropriate for further clinical development.
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