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Mesenchymal Stromal Cells
MSC Therapy for Asthma
Recruiting1 awardPhase 1
Atlanta, Georgia
This trial is designed to assess the safety and determine the maximal tolerated dose (MTD) of two different types of stem cells, allogenic cord tissue derived MSCs (cMSCs) and allogeneic, interferon-γ primed bone marrow MSCs (γMSCs). Each stratum is designed to independently accrue 3 children at a dose level 1 of 2x106 cells/kg and 6 children at dose level 2 of 10x106 cells/kg, resulting in 9 children in each stratum. The primary objectives are to determine the safety and toxicity of allogenic cord tissue derived MSCs and allogeneic
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