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Hormone Therapy
CGM + Insulin for Hypoglycemia Awareness in Type 1 Diabetes
Recruiting1 awardPhase < 1
New Haven, Connecticut
This trial assessed whether there are distinct differences in patterns of brain responses to hypoglycemia between type 1 diabetes patients who are aware of hypoglycemia (T1DM-Aware) and those who are unaware of it (T1DM-Unaware), and healthy controls. T1DM-Aware patients showed greater activity in sensory integration brain regions (e.g. parietal lobe and caudate nucleus) in response to hypoglycemia, whereas T1DM-Unaware patients showed no detectable changes in brain reward regions during hypoglycemia.
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