Transgender Clinical Trials
Here are the 6 most popular medical studies for transgender
Behavioral Intervention
Interpersonal Psychotherapy for Alcoholism
This trial will study whether an adapted version of interpersonal psychotherapy (IPT) is an effective treatment for alcohol use disorder (AUD) in gender minority (GM) individuals. GM individuals experience disproportionately high rates of hazardous drinking and AUD, and there are no evidence-based alcohol interventions for this population. The study will use mixed-methods formative research with an established multi-site longitudinal GM cohort to develop and assess the feasibility of the adapted IPT intervention.
Hormone Therapy
Testosterone for Health Services for Transgender Persons
The trial studies the efficacy of subcutaneous (SQ) testosterone compared to intramuscular (IM) testosterone therapy during the first 6 months of pubertal induction in transgender male adolescents. Describes rate of adverse effects, masculinizing effects and quality of life while receiving testosterone. Evaluates clinic utilization required for testosterone therapy.
Antiretroviral Agent
Long-acting PrEP Injections + Adherence App for HIV Prevention in Transgender Women
This trial will test if transgender women (TW) can use tailored injection strategies, such as self-injection or injection by a healthcare provider at "drop-in clinics", to improve adherence to HIV prevention medication, compared to a control group of TW.
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HIV Clinical Trials
View 10 HIV medical studies.
Behavioural Intervention
Mobile App Intervention for Risky Alcohol Use
This trial will use mobile apps to deliver messages to reduce risky drinking & HIV risk in sexual minority males & transgender persons. They'll also take surveys & breathalyzer readings to measure outcomes.
Antiretroviral
PrEP for HIV Prevention in Transgender Individuals
This trial will study PrEP levels in trans/non-binary folks taking gender-affirming hormones. They'll get personalized text reminders and take F/TAF for 48 weeks. 60 people will be enrolled.
Behavioural Intervention
ENTRUST for AIDS
This trial aims to test the idea that helping transgender women with financial stability and counseling will make it more likely for them to use substance abuse and HIV prevention services. Additionally, it will see if transgender women
Transgender Clinical Trials With No Placebo
View 33 transgender medical studies that do not have a placebo group.
Behavioural Intervention
Online Intervention for Gender Dysphoria
This trial seeks to reduce symptoms of gender dysphoria & improve well-being for trans & nonbinary individuals through an online intervention (Trans Care). A randomized controlled trial will enroll 260 TNB participants.
Behavioral Intervention
GAP Training for Mental Health Provider Education
This trial aims to improve mental health care for gender minority youth by testing an intervention to increase providers' use of gender-affirming practices. A future RCT will assess feasibility and acceptability.
Behavioural Intervention
Mobile App Intervention for Risky Alcohol Use
This trial will use mobile apps to deliver messages to reduce risky drinking & HIV risk in sexual minority males & transgender persons. They'll also take surveys & breathalyzer readings to measure outcomes.
View More Transgender Trials
See another 10 medical studies focused on transgender.
Frequently Asked Questions
Introduction to transgender
What are the top hospitals conducting transgender research?
In recent years, there has been a growing recognition of the unique healthcare needs of transgender individuals. Hospital institutions across the United States have taken strides to address these needs through clinical trials focusing on transgender health. One such institution is the University of Wisconsin in Madison, which currently has three ongoing trials specifically dedicated to transgender patients. Although relatively new to this field, with only two recorded trials thus far and their first trial documented in 2024, their commitment to advancing transgender healthcare is commendable.
Moving over to the West Coast, San Francisco’s Bridge HIV CRS plays a pioneering role in addressing the medical concerns faced by transgender individuals. With two active clinical trials underway and no previous recorded studies exclusively focused on transgender health, this hospital demonstrates a forward-thinking approach that aims to bridge gaps in knowledge regarding effective interventions for this community.
Similarly, New york's Harlem Prevention Center CRS and Philadelphia's Penn Prevention CRS are also actively engaged in two ongoing transgender clinical trials each but do not have any prior history of conducting specific research for gender-affirming healthcare before now.
Meanwhile, Houston AIDS Research Team CRS stands as another key player striving towards improving trans-inclusive care by running two current clinical studies centered around transgender participants but like some others mentioned hasn't conducted any past investigations related solely toward this population till date.
These hospitals signify significant progress within the medical community when it comes to acknowledging and accommodating diverse identities within healthcare research. By devoting resources and expertise toward understanding and addressing the unique challenges faced by transgender individuals, these institutions are driving advancements that will ultimately lead to a more inclusive and supportive future for all members of society.
Which are the best cities for transgender clinical trials?
When it comes to transgender clinical trials, several cities stand out as hubs for research and development. New york, with its 16 active trials, offers studies like Group 1: BIC-treated and Arm A. Chicago follows closely behind with 7 ongoing trials focusing on interventions such as Focus Groups and F/TAF. Los Angeles also plays a significant role, hosting 6 active trials examining treatments like Prep N' Shine: Strength Based Case Management (Stage 1) and Surgery-specific general anesthetic + ultrasound guided peripheral nerve block #2. Lastly, San Francisco and Houston each have 5 active trials contributing to the advancement of transgender healthcare. These cities provide valuable opportunities for individuals in the transgender community to participate in cutting-edge clinical research that can lead to improved care options tailored specifically to their needs.
Which are the top treatments for transgender being explored in clinical trials?
In the realm of transgender healthcare, clinical trials are paving the way for innovative treatments. The top contenders currently being explored in these trials include:
- Hormone Replacement Therapy (HRT): Studying different hormone regimens and delivery methods to optimize physical transition
- Gender-Affirming Surgeries: Investigating techniques and outcomes of various surgical procedures like chest reconstruction or genital reconstruction
- Voice Therapy: Exploring interventions to help individuals modify their vocal pitch and resonance to align with their gender identity These ongoing studies aim to enhance the quality of care available for transgender individuals, providing them with more options and personalized treatment approaches.
What are the most recent clinical trials for transgender?
Exciting progress is being made in the field of transgender healthcare through recent clinical trials. One such trial investigates the effectiveness of Clascoterone, a potential treatment for individuals undergoing gender transition. This trial spans both Phase 1 and Phase 2, offering hope for enhanced hormone therapy options. Additionally, an ongoing Phase 4 study called Enhanced Implementation (EI) focuses on improving the implementation of transgender healthcare practices to ensure optimal outcomes and accessibility. Another significant trial explores surgery-specific general anesthesia combined with ultrasound-guided peripheral nerve block #2 as a means to improve surgical experiences for transgender patients. Furthermore, a Phase 2 study examines the efficacy of twice-daily sublingual estradiol plus spironolactone in hormone therapy regimens tailored specifically towards transgender individuals. These groundbreaking trials mark important steps forward in enhancing care and well-being within the transgender community.
What transgender clinical trials were recently completed?
Recently completed clinical trials have focused on advancing transgender healthcare and addressing the unique needs of this community. Notable among them is a trial conducted by University College London that investigated hormone therapy for transgender individuals, with results expected to shape future treatment approaches. Another significant study, led by The Fenway Institute in Boston, examined the impact of gender-affirming surgeries on mental health outcomes in transgender people. These groundbreaking trials contribute valuable insights into improving the overall well-being and quality of care for transgender individuals.