Dysphagia Clinical Trials
Here are the 6 most popular medical studies for dysphagia
EMST for Swallowing Disorders in Head and Neck Cancer Patients
This trial is testing whether expiratory muscle strength training can help people with cancer of the head and neck who are undergoing radiation therapy or chemoradiotherapy to maintain efficient and safe swallowing function.
Behavioural Intervention
Wearable Sensor Monitoring for Cervical Spine Fusion Recovery
This trialwill test a noninvasive, skin-like electronic sensor to monitor recovery of patients who've had ACDF surgery. Physiological signals like heart rate, respiratory rate, and more will be measured.
Behavioural Intervention
Expiratory Muscle Training for Swallowing Disorders
This trial will test whether a modified 8-week expiratory muscle strength training program can help improve swallowing safety and lung function in elderly veterans with swallowing disorders, compared to no intervention.
Corticosteroid
Steroid for Swallowing Difficulty
This trial looks at whether a single dose of a steroid given intravenously can improve swallowing function after anterior cervical spine surgery, compared to a control group who received a saline solution.
Popular filter options for dysphagia trials
Swallowing Difficulty Clinical Trials
View 25 Swallowing Difficulty medical studies.
Behavioral Intervention
ESSI-SURG +1 More for Swallowing Difficulty
This trial will examine whether early and systematic speech and swallowing therapy with speech-language pathologists can help improve the health and function of patients with oral cavity cancer, specifically tongue cancer, who are undergoing surgery.
Behavioral Intervention
Prophylactic Swallow Intervention for Head and Neck Cancer
This trial will compare the effectiveness of PRO-ACTIVE (high and low intensity) versus RE-ACTIVE swallowing therapy among 952 patients with HNC planning to undergo RT, using duration of feeding tube dependence after RT as the primary outcome.
Procedure
Codetron ALTENS for Head and Neck Cancers
Study hypothesis: ALTENS techniques, administered within the first 3 months after radiation completion, can improve radiation-induced dysphagia and associated symptoms in head and neck cancer patients. This beneficial effect is mediated by the reduction of chronic inflammatory response of swallowing musculature to radiation, consequently a reduction in muscle fibrosis. Primary study objective: To evaluate the effectiveness of ALTENS in relieving radiation-induced dysphagia. Eating Assessment Tool (EAT-10) scores will be used for this primary study endpoint.
Achalasia Clinical Trials
View 25 Achalasia medical studies.
Behavioral Intervention
ESSI-SURG +1 More for Swallowing Difficulty
This trial will examine whether early and systematic speech and swallowing therapy with speech-language pathologists can help improve the health and function of patients with oral cavity cancer, specifically tongue cancer, who are undergoing surgery.
Behavioral Intervention
Prophylactic Swallow Intervention for Head and Neck Cancer
This trial will compare the effectiveness of PRO-ACTIVE (high and low intensity) versus RE-ACTIVE swallowing therapy among 952 patients with HNC planning to undergo RT, using duration of feeding tube dependence after RT as the primary outcome.
Procedure
Codetron ALTENS for Head and Neck Cancers
Study hypothesis: ALTENS techniques, administered within the first 3 months after radiation completion, can improve radiation-induced dysphagia and associated symptoms in head and neck cancer patients. This beneficial effect is mediated by the reduction of chronic inflammatory response of swallowing musculature to radiation, consequently a reduction in muscle fibrosis. Primary study objective: To evaluate the effectiveness of ALTENS in relieving radiation-induced dysphagia. Eating Assessment Tool (EAT-10) scores will be used for this primary study endpoint.
Dysphagia Clinical Trials With No Placebo
View 38 dysphagia medical studies that do not have a placebo group.
Behavioral Intervention
ESSI-SURG +1 More for Swallowing Difficulty
This trial will examine whether early and systematic speech and swallowing therapy with speech-language pathologists can help improve the health and function of patients with oral cavity cancer, specifically tongue cancer, who are undergoing surgery.
Interbody Cage
ACDF interbody cage +1 More for Cervical Radiculopathy
This trial aims to compare the outcomes of two different types of interbody cages used during a surgical procedure called ACDF. One group of patients will receive a cage with a specific technology called nanoLOCK os
Behavioural Intervention
Lingual Exercises for Post-Stroke Swallowing Disorders
This trial will enroll 15 participants in each of three exercise conditions in order to study the feasibility and efficacy of lingual endurance training to improve aspects of swallowing for those with persistent dysphagia after ischemic stroke. The three groups are: 1) lingual endurance training, 2) lingual endurance training + transference exercise, and 3) no exercise. The primary outcome measures are patient adherence and improvement on videofluoroscopic assessment of swallowing function. Secondary outcome measures include oropharyngeal residue, airway invasion, and patient reported swallowing quality of life.
Behavioral Intervention
Prophylactic Swallow Intervention for Head and Neck Cancer
This trial will compare the effectiveness of PRO-ACTIVE (high and low intensity) versus RE-ACTIVE swallowing therapy among 952 patients with HNC planning to undergo RT, using duration of feeding tube dependence after RT as the primary outcome.
View More Dysphagia Trials
See another 23 medical studies focused on dysphagia.
Frequently Asked Questions
Introduction to dysphagia
What are the top hospitals conducting dysphagia research?
Finding effective treatments for dysphagia, a condition characterized by difficulty swallowing, requires dedicated research and innovation. Hospitals across the United States and Canada are spearheading efforts to improve the lives of individuals with dysphagia through clinical trials. In Hines, Illinois, the Edward Hines Jr. VA Hospital has taken an active role in this pursuit with two ongoing dysphagia trials and a total of two recorded trials since 2018. Similarly, Froedtert Hospital in Milwaukee has made significant contributions, conducting two current dysphagia trials and recording their first trial in 2017. Teachers College at Columbia University is also making strides in dysphagia research with two active trials and a history that dates back to their inaugural study in 2016.
Across state lines into Chicago, Northwestern Memorial Hospital is joining the fight against dysphagia with two ongoing clinical trials while commencing its earliest trial just this year (2022). Meanwhile on Canadian soil at Centre Hospitalier de l'Université de Montréal situated within Montreal; researchers are actively running dual specific investigations as well as having previously conducted around one initial experiment which marked successful commencement back from 2011.
These hospitals demonstrate unwavering commitment to advancing our understanding of dysphagia and developing new treatment options for those affected by this debilitating condition. Through collaboration between medical professionals and patients participating in these cutting-edge clinical trials, we move closer towards improving quality of life for individuals impacted by dysphagia worldwide
Which are the best cities for dysphagia clinical trials?
When it comes to dysphagia clinical trials, several cities emerge as hubs for research and innovation. New york, with its 4 active trials, explores interventions such as PRO-ACTIVE EAT + EXERCISE and Cough Skill Training. Cincinnati follows closely behind with 3 ongoing studies focused on Lingual Endurance + Transference Exercise and standard of care lingual strengthening. Additionally, Madison in Wisconsin also has 3 active trials investigating treatments like Isometric tongue strengthening facilitated by Iowa Oral Performance Instrument (IOPI). These cities offer individuals with dysphagia access to cutting-edge clinical trials that aim to improve swallowing function and quality of life through innovative approaches.
Which are the top treatments for dysphagia being explored in clinical trials?
Dysphagia, a swallowing disorder, is the focus of ongoing clinical trials investigating potential treatment options. Noteworthy treatments being explored include:
- Autologous Muscle Derived Cells for Gastro-Intestinal Repair (AMDC-GIR): Currently involved in two active dysphagia trials since its listing in 2017.
- Lingual Endurance + Transference Exercise: One active trial underway as researchers investigate its efficacy in managing dysphagia symptoms.
- Ice chips: This unconventional option also has one active trial dedicated to examining its impact on dysphagia management.
- Standard of care lingual strengthening: Researchers are evaluating the effectiveness of this approach through an ongoing clinical trial initiated in 2021.
- Expiratory Muscle Strength Training (EMST): With one active dysphagia trial and first listed in 2018, EMST holds promise as a potential treatment.
As these trials progress and results emerge, they offer hope for improved outcomes and better quality of life for individuals suffering from dysphagia.
What are the most recent clinical trials for dysphagia?
Exciting advancements are being made in the field of dysphagia research, offering hope for individuals struggling with swallowing difficulties. One recent clinical trial investigates a virtual group speech therapy intervention guided by a patient partner, providing an innovative approach to address dysphagia. Another study focuses on Cough Skill Training specifically designed for this condition. Additionally, telehealth has emerged as a valuable tool in managing dysphagia, allowing patients to receive remote support and guidance from healthcare professionals. Moreover, researchers are exploring the potential of Autologous Muscle Derived Cells for Gastro-Intestinal Repair (AMDC-GIR) in treating dysphagia-related issues. Although ongoing efforts continue to pave the way forward in understanding and combating dysphagia, it is important to note that experimental radiotherapy +/- chemotherapy has also shown promising results as part of comprehensive treatment plans against this debilitating condition.
What dysphagia clinical trials were recently completed?
Recently, several important clinical trials focusing on dysphagia have been completed. These trials aimed to advance our understanding and treatment of this swallowing disorder. The results will provide valuable insights into potential interventions for individuals struggling with dysphagia, improving their quality of life and overall health.