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Dermal Filler

Hyaluronic Acid Fillers for Facial Volume Loss (RES Trial)

N/A
Waitlist Available
Led By Steven F Weiner, MD
Research Sponsored by Galderma R&D
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 4 weeks, 6 months, 9 months, and 12 months after baseline
Awards & highlights

RES Trial Summary

This trial looked at how well two types of Hyaluronic Acid fillers show up on ultrasound imaging.

Who is the study for?
This trial is for individuals who can consent to participate, will follow the study's procedures, and have midface volume loss. It excludes those with previous permanent facial implants, recent facial treatments in the last 6 months that could affect results, or allergies to lidocaine and hyaluronic acid.Check my eligibility
What is being tested?
The study aims to compare how two different Hyaluronic Acid dermal fillers – Restylane Contour and Juvederm Voluma – accumulate in tissue when observed under ultrasound after being injected into participants' midfaces.See study design
What are the potential side effects?
While not explicitly listed here, common side effects of dermal fillers include swelling, redness at injection sites, bruising, pain or tenderness. Rarely they may cause allergic reactions or lumpiness.

RES Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~immediately post-treatment, 4 weeks, 6 months, 9 months, and 12 months after baseline
This trial's timeline: 3 weeks for screening, Varies for treatment, and immediately post-treatment, 4 weeks, 6 months, 9 months, and 12 months after baseline for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Assess and compare tissue aggregation and visualization of Hyaluronic Acid fillers using ultrasound
Secondary outcome measures
Evaluate subject satisfaction using self-assessment questionnaire
Evaluate volume change in the treated areas using 3D imaging

RES Trial Design

2Treatment groups
Active Control
Group I: Juvederm VolumaActive Control1 Intervention
Form: sterile, biodegradable, non-pyrogenic, viscoelastic, clear, colorless, homogenous gel implant of Hyaluronic Acid crosslinked with BDDE, formulated with lidocaine. Mode of administration: injection Dosage: at investigator's discretion for optimal outcome. Frequency and duration: injection at baseline and optional touch-up at week 4.
Group II: Restylane ContourActive Control1 Intervention
Form: transparent gel of Hyaluronic Acid with the addition of lidocaine hydrochloride. Mode of administration: injection Dosage: at investigator's discretion for optimal outcome. Frequency and duration: injection at baseline and optional touch-up at week 4.

Find a Location

Who is running the clinical trial?

Galderma R&DLead Sponsor
300 Previous Clinical Trials
60,466 Total Patients Enrolled
Steven F Weiner, MDPrincipal InvestigatorThe Aesthetic Clinique

Media Library

Juvederm Voluma (Dermal Filler) Clinical Trial Eligibility Overview. Trial Name: NCT05622851 — N/A
Midface Volume Deficiency Research Study Groups: Juvederm Voluma, Restylane Contour
Midface Volume Deficiency Clinical Trial 2023: Juvederm Voluma Highlights & Side Effects. Trial Name: NCT05622851 — N/A
Juvederm Voluma (Dermal Filler) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05622851 — N/A
~4 spots leftby Jun 2025
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