Your session is about to expire
← Back to Search
Focused Ultrasound Pallidotomy for Parkinson's Disease
Study Summary
This trial will test whether a new treatment for Parkinson's disease, focused ultrasound pallidotomy, is safe and effective.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
Find a Location
Who is running the clinical trial?
Media Library
- I have been on the same antidepressant for at least 3 months.You can tell how you are feeling during the procedure.My Parkinson's disease is advanced, affecting my physical movements even with medication.I have been diagnosed with a neurodegenerative disease like Alzheimer's.I have a condition that causes abnormal bleeding or blood clotting issues.I have had a seizure in the last year.I am 30 years old or older.My Parkinson's disease symptoms are severe without medication or I have complications despite treatment.My heart condition is stable.My blood pressure is very high even with medication.I have not taken blood thinners or certain medications that increase bleeding risk within the required time before a focused ultrasound procedure.I cannot or do not want to stay lying down for a long time.You have low platelet count, a blood clotting problem, or abnormal INR coagulation test results.I have severe claustrophobia that medication cannot help.I need treatment for an intracranial aneurysm or AVM.I have been diagnosed with Parkinson's disease by a specialist.My Parkinson's symptoms are severe without medication or I have complications despite treatment.My Parkinson's disease medication dose has been stable for the last 30 days.I think my Parkinson-like symptoms might be due to my medication.I have a brain tumor.I can communicate how I feel during the ExAblate procedure.You have conditions that make it unsafe for you to have a magnetic resonance imaging (MRI) scan.I have had a brain bleed, multiple strokes, or a stroke in the last 6 months.My Parkinson's symptoms improve by at least 30% when I take my medication.You have significant trouble with memory and thinking, as measured by a test called MMSE, and scored 24 or lower.You have been dependent on alcohol or drugs within the past year.I do not have uncontrolled mental health issues like severe depression or hallucinations.I have had deep brain stimulation or specific brain surgery.I have kidney disease or am on dialysis.
- Group 1: ExAblate Pallidotomy
- Group 2: Sham ExAblate Pallidotomy
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
How many sites are actively managing this research endeavor?
"This research initiative is recruiting patients from the Pennsylvania Hospital Department of Neurosurgery in Philadelphia, Swedish Medical Center in Seattle and Mayo Clinic in Rochester. Plus, there are 12 additional clinical trial sites across America."
Are there still vacancies available for prospective participants in this trial?
"The information on clinicaltrials.gov indicates that this particular research effort is now closed to recruitment, having first been posted on February 9th 2018 and last updated November 5th 2020. Nevertheless, there are over 500 other medical studies actively recruiting participants at the moment."
Who else is applying?
What state do they live in?
What site did they apply to?
What portion of applicants met pre-screening criteria?
How many prior treatments have patients received?
Share this study with friends
Copy Link
Messenger