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Procedure

Standard Percutaneous Nephrolithotomy (sPCNL) for Kidney Stones

N/A

Recruiting

Research Sponsored by University of California, San Diego

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up postoperative period, 24 hours on average.

Awards & highlights

Study Summary

This trial will compare the outcomes of two different procedures for treating renal stones - standard PCNL and mini-PCNL. The goal is to provide guidance on which procedure is better in the US population, and to study the safety and costs of each procedure.

Eligible Conditions

Kidney Stones

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ postoperative period, 24 hours on average.

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~postoperative period, 24 hours on average.

This trial's timeline: 3 weeks for screening, Varies for treatment, and postoperative period, 24 hours on average. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Blood Loss

Secondary outcome measures

Anesthesia Time

ED Visits

Hospital Stay Time

+14 more

Trial Design

2Treatment groups

Active Control

Group I: Standard Percutaneous Nephrolithotomy (sPCNL)Active Control1 Intervention

The first arm will consist of a Standard of Care standard percutaneous nephrolithotomy (sPCNL)- performed using a 30 Fr access sheath following balloon dilation.

Group II: Minimally Invasive Percutaneous Nephrolithotomy (MIP)Active Control1 Intervention

The second arm will consist of a Standard of Care mini percutaneous nephrolithotomy (mPCNL)- performed using an 18 Fr access sheath following either balloon dilation or dilation using a single step metal dilator.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of California, San DiegoLead Sponsor

1,123 Previous Clinical Trials

1,552,749 Total Patients Enrolled

5 Trials studying Kidney Stones

3,622 Patients Enrolled for Kidney Stones

Manoj Monga, M.D.Study ChairUCSD Medical Center, San Diego

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many medical centers are conducting this clinical trial?

"There are 6 trial sites that are currently running the study, such as Mayo Clinic in Phoenix, Vanderbilt University Medical Center in Nashville and University Of British Columbia in Vancouver. Other locations include..."

Answered by AI

How many participants is the medical trial currently accommodating?

"This clinical trial necessitates 90 eligible individuals to be recruited from different locations, such as Mayo Clinic in Phoenix and Vanderbilt University Medical Center in Nashville. To qualify for the study, each participant must meet specific inclusion criteria."

Answered by AI

What is the current status of recruitment for this trial?

"Affirmative. According to the clinicaltrials.gov database, this clinical trial is currently in search of volunteers and was initially posted on January 15th 2021 with a most recent update on July 12th 2022. 90 participants are needed across 6 different sites."

Answered by AI

Recent research and studies

World Journal of UrologyJournal

A Prospective Comparative Study of Haemodynamic, Electrolyte, and Metabolic Changes During Percutaneous Nephrolithotomy and Minimally Invasive Percutaneous Nephrolithotomy

Xu, Shuxiong, Hua Shi, Jianguo Zhu, Yuanlin Wang, Ying Cao, Kai Li, Yandong Wang, Zhaolin Sun, and Shujie Xia. 2013. “A Prospective Comparative Study of Haemodynamic, Electrolyte, and Metabolic Changes During Percutaneous Nephrolithotomy and Minimally Invasive Percutaneous Nephrolithotomy”. World Journal of Urology. Springer Science and Business Media LLC. doi:10.1007/s00345-013-1204-2.

UrolithiasisJournal

Minimally Invasive Percutaneous Nephrolithotomy Vs Standard PCNL for Management of Renal Stones in the Flank-free Modified Supine Position: Single-center Experience

Sakr, Ahmed, Emad Salem, Mostafa Kamel, Esam Desoky, Ahmed Ragab, Mohamed Omran, Amr Fawzi, and Ashraf Shahin. 2017. “Minimally Invasive Percutaneous Nephrolithotomy Vs Standard PCNL for Management of Renal Stones in the Flank-free Modified Supine Position: Single-center Experience”. Urolithiasis. Springer Science and Business Media LLC. doi:10.1007/s00240-017-0966-1.

Journal of EndourologyJournal

Does a Smaller Tract in Percutaneous Nephrolithotomy Contribute to High Renal Pelvic Pressure and Postoperative Fever?

Zhong, Wen, Guohua Zeng, Kaijun Wu, Xun Li, Wenzhong Chen, and Houmeng Yang. 2008. “Does a Smaller Tract in Percutaneous Nephrolithotomy Contribute to High Renal Pelvic Pressure and Postoperative Fever?”. Journal of Endourology. Mary Ann Liebert Inc. doi:10.1089/end.2008.0001.

European UrologyJournal