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Genome Sequencing for Personalized Cancer Therapy
Study Summary
This trial will use full genome sequencing to identify cancer "drivers" and corresponding drugs that may inhibit these pathways, in order to match each individual cancer to a biologically relevant targeted therapy.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I am open to being contacted for future studies and believe I would be fit for clinical trials.My organs are working well.I agree to let my stored tissue samples be used for research, even if they are all used up.I do not want to know about specific genetic findings from my tests.I am fully active or restricted in physically strenuous activity but can do light work.I agree to give a blood sample for genetic testing.I am 18 years old or older.I can provide a recent biopsy or have suitable stored tissue samples for the study.I understand my data will guide my treatment, possibly avoiding or suggesting certain therapies.I agree to share my anonymous genetic and health information for research.My doctor thinks I can participate in a treatment study soon and live at least 6 more months.
- Group 1: Genome Sequencing
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Is the participant eligibility for this research restricted to those aged sixty and above?
"This research project is seeking participants between 18 and 85 years old. To date, there are 50 studies for minors and 815 studies involving seniors aged 65 or older."
How many individuals have enrolled in this experiment?
"Yes, the records found on clinicaltrials.gov confirm that this medical trial is enrolling subjects at present. The study was initially posted online on July 1st 2014 and has since been updated as of January 26th 2021. 5000 participants are sought from one location for this investigation."
Is there still an opportunity for individuals to enroll in the clinical trial?
"The data hosted on clinicaltrials.gov reveals that this trial is currently seeking participants, with the initial posting made on July 1st 2014 and updated as recently as January 26th 2021."
Who has been determined to be a suitable candidate for this research endeavor?
"This clinical trial is enlisting 5000 individuals aged between 18 and 85 who possess malignant neoplasms. To be eligible for participation, patients must agree to have their archival specimens used (and possibly depleted) for research purposes; they should also consent to providing a blood sample or other normal DNA specimen for germline genomic study; exhibit an Eastern Cooperative Oncology Group performance status of 0 or 1; exceed the age of majority; expect more than 6 months life expectancy while remaining clinically fit in 3-6 months' time; demonstrate measurable disease by RECIST v1.1 criteria or later version thereof, as well as adequate organ function"
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