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Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 3 days before removal of exercise
Awards & highlights
Study Summary
This trial aims to study how a short period of not exercising affects blood sugar levels and blood vessel function in active older adults. The researchers want to see if taking a break from exercise leads to problems with
Who is the study for?
This trial is for healthy, physically active older adults aged 55 and above who currently exercise at least 90 minutes per week. It's also open to those between 18-40 years old. Participants should not have physical limitations that could affect changes in their daily activity levels.Check my eligibility
What is being tested?
The study aims to see if stopping exercise briefly affects blood sugar control and blood vessel health in older adults who usually stay active. Researchers will check how fast these effects happen with no exercise, and if going back to exercising for three days can reverse any negative impacts.See study design
What are the potential side effects?
Since the intervention involves removing exercise rather than adding a drug or medical procedure, typical medication side effects are not expected. However, participants may experience changes in mood, energy levels, sleep patterns or temporary alterations in metabolism.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 3 days before removal of exercise
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~3 days before removal of exercise
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Continuous glucose monitoring
Flow mediated dilation
Flow mediated dilation (vascular health)
Trial Design
2Treatment groups
Experimental Treatment
Group I: VascularExperimental Treatment1 Intervention
Vascular: Participants will have their blood vessel health measured while performing their normal exercise routines (EX) and while undergoing 1, 3, 5 days of no exercise (NOEX) followed immediately by 1 and 3 days of return to exercise (REX).
Group II: MetabolicExperimental Treatment1 Intervention
Metabolic: Participants will have their blood glucose levels measured via continuous glucose monitoring for 3 days while participating in their normal exercise routines (EX). Participants will also have their blood glucose levels measured for 3 days while not exercising (NOEX), following immediately by 3 days of a return to normal activity(REX). Participants will be randomized to participate in the EX or NOEX/REX phases first. The EX and NOEX/REX phases will be separated by at least 1 week
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Who is running the clinical trial?
Old Dominion UniversityLead Sponsor
21 Previous Clinical Trials
15,034 Total Patients Enrolled
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