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Cognitive Training for Alzheimer's Disease (PACT Trial)
PACT Trial Summary
This trial will test if a cognitive training technique can help delay the onset of mild cognitive impairment or dementia.
PACT Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowPACT Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.PACT Trial Design
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Who is running the clinical trial?
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- I can read from a computer screen at a normal distance.I can use a computer mouse or touch a screen.You do not have any mental health conditions that would make it hard for you to follow the study instructions or benefit from the treatment.I understand and can follow the study's procedures.I have vision, hearing, or motor issues that could affect my participation in the study.I can speak and understand English or Spanish.You are already participating in another research study that involves testing cognitive abilities.I can use a computer mouse or touch a screen.I have a condition like mild cognitive impairment or dementia that affects my thinking.I am taking medication for dementia.I am 65 years old or older.I can use a computer for exercises without help.I am experiencing severe depression.I can use a computer for exercises without help.I am 65 years old or older.I can speak and understand English or Spanish.I can hear and understand normal conversation.I have completed over 10 hours of a recognized brain training program in the last 5 years.I can read from a computer screen at a normal distance.You have already taken part in a study that involved cognitive training in the past.I can hear and understand normal conversation.
- Group 1: Computerized Cognitive Training
- Group 2: Computerized Cognitive Stimulation
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Pivotal Trial - The final step before approval, pivotal trials feature drugs that have already shown basic safety & efficacy.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Is this research project limited to only a few US states, or are there plans to expand it?
"Currently, there are 7 operational clinical trial sites. These locations are in Tucson, Gainesville and Jacksonville as well as 4 other cities. If you are considering participating in this study, it might be most convenient for you to select a location nearest you to limit travel requirements."
How many people will be able to participate in this research project?
"To run this experiment, 7600 individuals that fit the pre-determined inclusion criteria are required. Patients have the opportunity to participate at Banner Alzheimer's Institute Tucson in Tucson or University of Florida in Gainesville."
Are individuals still being recruited for this trial?
"From what is detailed on clinicaltrials.gov, it seems that this study is still looking for participants. The original posting was on February 19th, 2019 with the most recent edit being from March 24th, 2022."
Does the FDA recognize Cognitive Training as an accepted medical treatment?
"There is some evidence to support the efficacy of Cognitive Training, as this is a Phase 3 trial. Furthermore, because there have been multiple rounds of data supporting safety, our team at Power has estimated the safety to be a 3 on a scale from 1 to 3."
Who else is applying?
What state do they live in?
How old are they?
What site did they apply to?
What portion of applicants met pre-screening criteria?
How responsive is this trial?
Average response time
- < 2 Days
Typically responds via
Most responsive sites:
- Duke Health: < 48 hours
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