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Acetaminophen for Osteoarthritis

Phase 4

Recruiting

Research Sponsored by Indiana Hand to Shoulder Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 2 weeks

Awards & highlights

Study Summary

This trial will examine different pain relief regimens to decrease the amount of opioids prescribed after a common hand surgery.

Who is the study for?

This trial is for adults with painful thumb arthritis (Eaton Classification stage II-IV) who are planning to have surgery within 6 months. Candidates must have bilateral thumbs affected and no history of liver dysfunction, previous thumb surgeries, allergies to acetaminophen or multivitamins, opioid dependency, or conditions that contraindicate nerve blocks.Check my eligibility

What is being tested?

The study tests if high doses of Acetaminophen before and after thumb surgery can reduce the need for opioids. Participants will either receive Acetaminophen or a placebo multivitamin in a randomized manner to compare their effects on pain management post-surgery.See study design

What are the potential side effects?

Acetaminophen may cause side effects such as nausea, itching, shortness of breath if allergic reactions occur; however it's generally considered safe when used as directed. Overuse can lead to liver damage.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 2 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~2 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Narcotics

Visual Analogue Scale (VAS)

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Test GroupExperimental Treatment1 Intervention

: Preoperative acetaminophen and postoperative standardized pain management regimen

Group II: Control GroupPlacebo Group1 Intervention

Preoperative multivitamin and postoperative standardized pain management regimen

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Acetaminophen

2017

Completed Phase 4

~2030

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Indiana Hand to Shoulder CenterLead Sponsor

8 Previous Clinical Trials

300 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What adverse effects could be experienced by members of the Test Group?

"We have assigned Test Group a rating of 3 on our safety scale, since Phase 4 trials indicate that this treatment has been approved."

Answered by AI

Are there any available vacancies for participants in this trial?

"Affirmative, the details hosted on clinicaltrials.gov indicate that this medical experiment is in search of participants. This trial was initially posted on September 13th 2022 and has since been updated on September 27th 2022. The study requires a total of 50 individuals to be recruited from one site."

Answered by AI

To what extent is the research population involved in this experiment?

"Affirmative. According to clinicaltrials.gov, the research project was created on September 13th 2022 and is still ongoing with updates taking place as recently as September 27th 2022. The team intends to recruit 50 patients from a single site for this study."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Effect of Perioperative Acetaminophen Dosing on Patients Undergoing Surgical Treatment of Basilar Thumb Arthritis

2022. "Effect of Perioperative Acetaminophen Dosing on Patients Undergoing Surgical Treatment of Basilar Thumb Arthritis". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05556356.