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Corticosteroid

dexamethasone for Cervicogenic Radiculopathy

Phase 2
Waitlist Available
Led By Timothy Amrhein, MD
Research Sponsored by Duke University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2 week, 3 months, 4 months
Awards & highlights

Study Summary

This trial is comparing two ways of giving epidural steroid injections to see if one is more effective or safe than the other for treating nerve pain in the arm.

Eligible Conditions
  • Cervicogenic Radiculopathy

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2 week, 3 months, 4 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 week, 3 months, 4 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Numerical Rating Scale (averaged over past 24 hours)
Secondary outcome measures
Change in EQ-5D
Change in NRS (averaged over past 24 hours)
Change in Neck Disability Index (NDI)
+13 more

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Lateralized Interlaminar Epidural Corticosteroid InjectionsExperimental Treatment1 Intervention
Group II: Transforaminal Cervical Epidural Corticosteroid InjectionsActive Control1 Intervention
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
dexamethasone
1995
Completed Phase 3
~9520

Find a Location

Who is running the clinical trial?

Duke UniversityLead Sponsor
2,375 Previous Clinical Trials
3,426,849 Total Patients Enrolled
Timothy Amrhein, MDPrincipal InvestigatorDuke University

Media Library

Dexamethasone (Corticosteroid) Clinical Trial Eligibility Overview. Trial Name: NCT03389620 — Phase 2
Cervicogenic Radiculopathy Research Study Groups: Transforaminal Cervical Epidural Corticosteroid Injections, Lateralized Interlaminar Epidural Corticosteroid Injections
Cervicogenic Radiculopathy Clinical Trial 2023: Dexamethasone Highlights & Side Effects. Trial Name: NCT03389620 — Phase 2
Dexamethasone (Corticosteroid) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03389620 — Phase 2

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any unfilled vacancies for those wishing to participate in this experiment?

"Correct. The clinicaltrials.gov website confirms that this medical experiment, which was first posted on May 1st 2018, is actively recruiting patients to participate. Approximately 116 participants are required from a single site for the study's completion."

Answered by AI

How many participants are joining the trial at this time?

"Yes, according to information posted on clinicaltrials.gov, this medical experiment is actively searching for participants since its inception on May 1st 2018 and the most recent update was made in February 2022. A total of 116 volunteers are necessary from one site only."

Answered by AI

What conditions is dexamethasone typically prescribed to treat?

"Dexamethasone has been proven to be a viable medical treatment for ophthalmia, sympathetic eye disorder, and branch retinal vein occlusion."

Answered by AI

Are there any prior investigations involving dexamethasone?

"Currently, 552 medical trials studying dexamethasone are ongoing worldwide; with 144 of those studies in the final phase of clinical data collection. The majority of these tests take place in Mishawaka, Indiana but there are 18604 locations running such research initiatives."

Answered by AI

What potential risks may be associated with dexamethasone treatment?

"Our team at Power assigned dexamethasone a score of 2 out of 3, as while there is evidence to suggest it is safe, the lack of efficacy data implies greater caution."

Answered by AI
~10 spots leftby May 2025