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Gene Therapy for Hemophilia A
Study Summary
This trial will test a new gene therapy for hemophilia A, which if effective could provide a much more convenient treatment option than current methods.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I am currently on medication for hepatitis B or C.I have or had high levels of Factor VIII inhibitors.My liver has significant scarring detected by a special scan.I do not have immunity to the AAV8 vector as tested by specific antibody tests.I have heart or genetic conditions that increase my risk for blood clots.I am a man aged 18 or older.I have received FVIII therapy for at least 150 days.I have had heart surgery and need blood thinners.I have received gene therapy.I have severe or moderately severe hemophilia A.I have a long-term kidney disease.I've had 12 or more bleeding episodes in the last year while on on-demand therapy.I do not have an active infection or a condition that weakens my immune system.
- Group 1: ASC618
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Are we able to enroll new patients in this research project at this time?
"The clinicaltrials.gov website indicates that this study is still looking for participants. This research was originally posted on August 1st, 2022 and updated 2 weeks ago on the 17th of August. So far, only 12 people have been recruited from a single location."
How many people will be included in this clinical research?
"That is correct, the online clinicaltrial.gov registry shows that this study is actively looking for participants. The trial was first announced on August 1st, 2022 and updated two weeks ago. So far, only 12 patients have been recruited from a single site."
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