PRP for Solar Elastosis

Phase 1 & 2

Waitlist Available

Led By Murad Alam, MD

Research Sponsored by Northwestern University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 2 weeks, 3 months, 6 months, 12 months

Awards & highlights

Study Summary

This trial will test whether platelet-rich plasma injections can improve the appearance of photoaged skin, compared to saline injections. The study will be divided into two parts: safety/tolerability and effectiveness.

Who is the study for?

This trial is for men and women aged 35-60 who want to improve facial wrinkles. They must be in good health, understand the study, and consent to participate. Excluded are those with skin cancer history, active skin diseases or infections, immune system issues, blood disorders, recent cosmetic treatments or surgeries on the face, certain allergies like lidocaine allergy, genetic disorders affecting collagen or fibroblasts.Check my eligibility

What is being tested?

The study tests platelet rich plasma (PRP) against sterile saline injections for treating photoaged skin. It has two parts: one checks PRP's safety on the arm; the other compares PRP's effect on one side of the face versus saline on the other over twelve months.See study design

What are the potential side effects?

Potential side effects may include discomfort at injection sites, bruising, swelling or redness. There could also be a risk of infection at injection points and rare allergic reactions.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 2 weeks, 3 months, 6 months, 12 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~2 weeks, 3 months, 6 months, 12 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 weeks, 3 months, 6 months, 12 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Study Part 1: Safety and Tolerability

Study Part 2: Change in Photoaging scores from Baseline at 2 weeks, 3 months, and 6 months

Secondary outcome measures

Study Part 2: Rate of Adverse Events

Study Part 2: Self-Assessment

Study Part 2: Subject Satisfaction

+1 more

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Platelet Rich PlasmaExperimental Treatment1 Intervention

Concentrated blood platelets from subject will be injected multiple times into the superficial layer of either their arm (Part 1) or one side of their upper face and cheek (Part 2).

Group II: Sterile SalinePlacebo Group1 Intervention

Sterile saline will be injected multiple times into the superficial layer of either their arm (Part 1) or one side of their upper face and cheek (Part 2)that has not been injected with PRP.

Do I qualify?Apply below to find out