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Combination Therapy for Prostate Cancer
Study Summary
This trial will enroll patients with metastatic mCRPC who have not been previously treated with abiraterone or docetaxel.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I have moderate to severe nerve damage.I have previously been treated with apalutamide.I have not used any experimental drugs or had any invasive devices implanted in the last 4 weeks.I've had chemotherapy for advanced prostate cancer but no chemo for other diseases in the last 3 years.I have not had prostate surgery or treatment in the last 30 days.I have received beta-emitting bone-seeking radioisotope treatment.I have had adrenal insufficiency or hyperaldosteronism.I am allergic to specific cancer medications or their ingredients.My prostate cancer was confirmed by a lab test.I will stop taking herbal and alternative supplements before starting treatment, but I can continue with my daily multi-vitamin, calcium, and Vitamin D.My testosterone levels are below 50 ng/dL, and I am on hormone therapy unless I've had an orchiectomy.My blood and organ functions are within normal ranges.I can swallow pills without needing to crush, dissolve, or chew them.I have a long-term liver condition.I have been on a stable dose of bisphosphonates or Denosumab for at least 4 weeks.I can take care of myself and am up and about more than half of the day.I received radiation for prostate cancer less than 4 weeks ago.My cancer has spread to my brain.I haven't taken azole medications like Fluconazole in the last 2 weeks.I stopped taking any seizure-risk increasing meds 4 weeks before starting the study drug.My prostate cancer is worsening, shown by tests like PSA levels or scans.I haven't taken strong CYP3A4 drugs in the last 2 weeks.I have active or symptomatic viral hepatitis.I am older than 18 years.
- Group 1: All patients
- All Individual Drugs Already Approved - Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.
- Approved for 30 Other Conditions - This treatment demonstrated efficacy for 30 other conditions.
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
What is the aggregate number of participants in this experiment?
"This trial is no longer recruiting. It was first posted on December 30th 2016, and last updated on August 22nd 2022. For those seeking other studies involving prostate cancer, 1,258 trials are now open; meanwhile 686 clinical trials concerning Prednisone remain active for recruitment purposes."
Are there still available openings in this research endeavor?
"This trial is no longer recruiting patients. This particular clinical study was initially posted on December 30th, 2016 and most recently updated on August 22nd, 2022. For those looking for alternative trials to join, currently there are 1258 studies actively admitting participants afflicted with prostate cancer as well as 686 active Prednisone trials accepting applicants."
Has Prednisone been tested in other clinical trials prior to this one?
"Currently, there are 686 clinical studies active for Prednisone with 224 of them in their final phase. Most trials take place around Duarte, California but other medical centres across 39457 locations are also running experiments on this drug."
Has Prednisone been authorized by the FDA?
"The safety of Prednisone has been assessed and determined to be a 1 on a scale from 1-3 due to the limited data available for both its efficacy and security during this experimental phase."
In what types of treatment is Prednisone commonly prescribed?
"Prednisone is most commonly prescribed for thyroiditis, yet it may also be utilized in the management of prostate cancer non-metastatic, ulcerative colitis, and varicella-zoster virus acute retinal necrosis."
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