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Monoclonal Antibodies

VIP152 for Chronic Lymphocytic Leukemia

Phase 1
Waitlist Available
Research Sponsored by Vincerx Pharma, Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 3 years
Awards & highlights

Study Summary

This trial will test the safety and effectiveness of VIP152 in patients with CLL or Richter Syndrome.

Eligible Conditions
  • Chronic Lymphocytic Leukemia
  • Non-Hodgkin's Lymphoma
  • Richter Syndrome
  • MYC Amplification
  • MYC Overexpression
  • MYC Translocation

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 3 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 3 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Safety and Tolerability
Secondary outcome measures
Assessment of pharmacokinetics (PK) of VIP152
Duration of Response
Overall Response Rate
+2 more

Trial Design

2Treatment groups
Experimental Treatment
Group I: VIP152 in combination with BTKiExperimental Treatment2 Interventions
Investigating VIP152 in combination with a BTKi in patients with CLL
Group II: Monotherapy of VIP152Experimental Treatment1 Intervention
Investigating VIP152 in a monotherapy cohort in patients with high-risk CLL and Richter Syndrome

Find a Location

Who is running the clinical trial?

Vincerx Pharma, Inc.Lead Sponsor
3 Previous Clinical Trials
170 Total Patients Enrolled
Vincerx Study DirectorStudy DirectorVincerx Pharma, Inc.
3 Previous Clinical Trials
170 Total Patients Enrolled

Media Library

VIP152 (Monoclonal Antibodies) Clinical Trial Eligibility Overview. Trial Name: NCT04978779 — Phase 1
Chronic Lymphocytic Leukemia Research Study Groups: Monotherapy of VIP152, VIP152 in combination with BTKi
Chronic Lymphocytic Leukemia Clinical Trial 2023: VIP152 Highlights & Side Effects. Trial Name: NCT04978779 — Phase 1
VIP152 (Monoclonal Antibodies) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04978779 — Phase 1
~2 spots leftby May 2025