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Cranberry Juice for Preventing UTIs
N/A
Recruiting
Led By Liwei Gu, PhD
Research Sponsored by University of Florida
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Healthy women participants
At least 110 pounds in weight
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline and 21 days of each intervention
Awards & highlights
Study Summary
This trial will help researchers understand how cranberry intake can help prevent UTIs by looking at gut microbes and urinary biomarkers.
Who is the study for?
This trial is for healthy women who are prone to urinary tract infections (UTIs). Participants should weigh at least 110 pounds with a BMI between 18.5-29.9 kg/m2. Women who are pregnant, breastfeeding, have significant health issues, take medications that could affect the study's outcome, or have a BMI of 30 or higher cannot join.Check my eligibility
What is being tested?
The study is testing if drinking cranberry juice can prevent UTIs in women likely to get them by increasing urine's anti-adhesion properties against E. coli bacteria. It will also identify gut microbes and biomarkers related to this effect.See study design
What are the potential side effects?
Cranberry juice is generally safe but may cause mild stomach upset or diarrhea in some people. The placebo juice is unlikely to cause side effects.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I am a healthy woman.
Select...
I weigh at least 110 pounds.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ baseline and 21 days of each intervention
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline and 21 days of each intervention
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Change in the anti-adhesion activity
Secondary outcome measures
Change in gut microbiomes
Change in urinary biomarkers
Trial Design
2Treatment groups
Experimental Treatment
Group I: Placebo juice consumptionExperimental Treatment1 Intervention
Participants will be provided placebo juice to consume for 21 days
Group II: Experimental: Cranberry juice consumptionExperimental Treatment1 Intervention
Participants will be provided cranberry juice to consume for 21 days
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Who is running the clinical trial?
University of FloridaLead Sponsor
1,350 Previous Clinical Trials
719,400 Total Patients Enrolled
Liwei Gu, PhDPrincipal InvestigatorUniversity of Florida
6 Previous Clinical Trials
280 Total Patients Enrolled
Yavuz Yagiz, PhDStudy DirectorUniversity of Florida
1 Previous Clinical Trials
32 Total Patients Enrolled
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Eligibility Criteria:
This trial includes the following eligibility criteria:- You are a regular smoker or consume alcohol frequently.Your body mass index (BMI) is within a healthy range.Your body mass index (BMI) is greater than or equal to 30, which means you are obese.I am a healthy woman.I am not taking any medication that could affect the study results.I weigh at least 110 pounds.
Research Study Groups:
This trial has the following groups:- Group 1: Experimental: Cranberry juice consumption
- Group 2: Placebo juice consumption
Awards:
This trial has 0 awards, including:Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
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