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Repetitive Transcranial Magnetic Stimulation
rTMS for Bipolar Disorder
Recruiting0 awards
San Diego, California
This trial is being conducted to test the effects of high-dose, spaced theta-burst transcranial magnetic stimulation (TMS) on depressive symptoms in patients with bipolar disorder (BPD) who have failed to respond to prior treatments. The null hypothesis is that there will be no difference in reductions in depressive symptoms between the active TMS group and the sham group. The alternative hypothesis is that, compared with sham, active TMS will result in a greater reduction in depressive symptoms. The study will also aim to identify biomarkers in cortical regions associated with BPD and to formulate a statistical model that may be able to predict BPD remission after
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