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Cancer Vaccine
Dendritic Cell Vaccine + Pembrolizumab for Brain Metastasis from Breast Cancer
Recruiting1 awardPhase 2
Buffalo, New York
This trial is testing a dendritic cell vaccine in patients with either triple negative breast cancer or HER2+ breast cancer that has spread to the brain. The vaccine is designed to boost the immune system to recognize and destroy the cancer cells. Pembrolizumab is also being given in this trial. Pembrolizumab is an "immune checkpoint inhibitor" which is designed to either "unleash" or "enhance" the cancer immune responses that already exist by either blocking inhibitory molecules" or by activating stimulatory molecules. The hope is that by giving both the vaccine and pembrolizumab, the cancer
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