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Procedure
Autologous peripheral blood mononuclear cells ex vivo depleted for reactive T cells for Graft-versus-Host Disease
Recruiting1 awardPhase 2
Montreal, Quebec
Phase II multicenter, Canadian only study - open to 25 subjects. Study open to subjects with steroid-refractory or dependent chronic graft vs host disease. Series of 6 aphereses and 28 re-infusions over 24 weeks. Primary endpoint is FFS at 24 weeks. Primary objective is to measure the efficacy of CARE (Continuous Alloreactive T-Cell depletion and Regulatory T-cell Expansion)
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