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Selective Serotonin and Norepinephrine Reuptake Inhibitor
Microbiome Influence on Drug Metabolism
Recruiting2 awardsPhase 1
Somerville, New Jersey
This trial will study how drugs are metabolized by the microbiome in humans, in parallel with preclinical studies. The investigators will be able to confirm the relevance of microbiome-derived metabolism in vivo, create microbiome-dependent PK profiles of the drugs, and establish methodology to capture the contribution of microbiome-derived metabolism to inter-individual variability in clinical drug PK profiles.
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