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Stem Cell Therapy
CNS10-NPC-GDNF for Amyotrophic Lateral Sclerosis
Recruiting1 awardPhase 1
Los Angeles, California
This trial is examining the safety of transplanting cells that have been engineered to produce GDNF into the motor cortex of patients with ALS. The cells, called CNS10-NPC-GDNF, are a type of stem cell that can become several different types of cells in the nervous system, including astrocytes. GDNF is a protein that promotes the survival of many types of neural cells. The investigational treatment has been tested in people by delivering it to the spinal cord, but this study will test if it is safe to deliver the cells to the motor cortex of the brain.
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